A SIMPLE METHOD FOR THE DETERMINATION OF CAPACITY FACTOR ON SOLID-PHASE EXTRACTION CARTRIDGES .1.

In this paper a simple experimental method for the rapid determination of capacity factors of phenolic compounds on off-line solid-phase ext raction cartridges is described. A model solution of the analytes is b rought into equilibrium with the SPE cartridge by recycling in a close d loop. The capacity factors are calculated from the adsorbed amounts which can be determined by a chromatographic method. The method is sho wn to give comparable results with those of the breakthrough experimen ts. The simplicity of the experimental arrangement as well as the low cost and unattended operation offer a viable alternative to the conven tional methods of the determination of capacity factors on SPE cartrid ges. Practical limitations of the proposed method are also considered.