ORAL HAIRY LEUKOPLAKIA IN AN HIV-NEGATIVE WOMAN WITH BEHCETS-SYNDROME

The first case of oral hairy leukoplakia in an HIV-negative patient wi th Behcet's syndrome is reported. The patient was a 47-year-old woman with bilateral lesions on the tongue. The clinic and histologic appear ances were typical of hairy leukoplakia, and Epstein-Barr virus was de monstrated in the epithelial cells by DNA in situ hybridization. The p atient had been on systemic steroid therapy for 15 years to control le sions of Behcet's syndrome. The literature now records 30 HIV-negative patients with hairy leukoplakia.