THE CLINICAL-VALUE OF SERUM TISSUE POLYPEPTIDE SPECIFIC ANTIGEN (TPS)IN BREAST-CANCER PATIENTS

Citation
Ab. Halim et al., THE CLINICAL-VALUE OF SERUM TISSUE POLYPEPTIDE SPECIFIC ANTIGEN (TPS)IN BREAST-CANCER PATIENTS, Journal of tumor marker oncology, 10(1), 1995, pp. 65-70
Citations number
23
Categorie Soggetti
Oncology
ISSN journal
08863849
Volume
10
Issue
1
Year of publication
1995
Pages
65 - 70
Database
ISI
SICI code
0886-3849(1995)10:1<65:TCOSTP>2.0.ZU;2-Q
Abstract
The aim of this work was to estimate the value of serum TPS in breast cancer patients. 118 females were included; 88 with breast cancer and 30 normal healthy controls. TPS was determined using the enzyme immuno assay reagents supplied by Beki Diagnostics AB, Bromma, Sweden. Result s of the study revealed that serum TPS was significantly elevated in t he breast cancer patients compared to the normal control group. At 100 % and 85% specificity, 37.5% and 53.4% of cancer patients showed value s above the cut-off levels of 140 U/l and 100 U/l respectively. Serial determination of TPS exhibited an excellent concordance with the clin ical state of cancer patients after radical mastectomy.