ENANTIOSEPARATION BY CAPILLARY ELECTROPHORESIS

Capillary electrophoresis (CE) recently has been shown to be a promisi ng technique for the separation of optically active substances. This a rticle describes the influence of the chiral selector on enantioselect ivity. The author presents four classes of chiral selectors used as ps eudostationary phases for direct enantioseparation using CE - host - g uest complexation, micellar solubilization, ligand-exchange complexati on, and polymer-based discrimination - and discusses their chiral reco gnition mechanisms. He also addresses possible future developments in this field.