Coronary artery disease is a frequent condition in dialysis patients a
nd - probably due to the atypical symptomatology - is frequently under
diagnosed. Noninvasive tests are of limited value in establishing diag
nosis, whereby arteriography is frequently necessary. Secondary prophy
laxis is the same as in nondialysis patients. Due to a high reocclusio
n rate following PTCA bypass grafting is the preferred therapeutical o
ption. When medical therapy is indicated, hemodialysis therapy should
be adapted to coexistent coronary artery disease by avoiding dialysis
hypotension and overhydration. In coronary patients renal anemia worse
ns coronary perfusions and should be treated targeting at least a hema
tocrit of 35%.