CDNA CLONING OF A THROMBOXANE A(2) RECEPTOR FROM RAT ASTROCYTES

Authors
KITANAKA J HASHIMOTO H SUGIMOTO Y SAWADA M NEGISHI M SUZUMURA A MARUNOUCHI T ICHIKAWA A BABA A
Citation
J. Kitanaka et al., CDNA CLONING OF A THROMBOXANE A(2) RECEPTOR FROM RAT ASTROCYTES, Biochimica et biophysica acta. Molecular cell research, 1265(2-3), 1995, pp. 220-223
Citations number
19
Categorie Soggetti
Biology,Biophysics
Journal title
Biochimica et biophysica acta. Molecular cell research → ACNP
ISSN journal
01674889
Volume
1265
Issue
2-3
Year of publication
1995
Pages
220 - 223
Database
ISI
SICI code
0167-4889(1995)1265:2-3<220:CCOATA>2.0.ZU;2-R
Abstract
A cDNA clone for rat thromboxane (TX) A(2) receptor was obtained from cultured astrocytes. The cDNA encodes a protein of 341 amino acids wit h seven putative transmembrane domains. The receptor is homologous wit h mouse and human TXA(2) receptors at 92.7% and 71.8%, respectively. E xpression of messenger RNA for the receptor was examined by reverse tr anscriptase-polymerase chain reaction, showing ubiquitous expression i n brain glial cells such as astrocytes, oligodendrocytes and microglia .