LIPID PLASMA-LEVELS AND PLASMODIUM-FALCIP ARUM INFECTION IN SAO-TOME

Changes in lipid plasma levels during malaria attacks have been propos ed for use in diagnosis or to assess the severity of the disease. In o rder to analyse the plasma levels of cholesterol, triglycerides, HDLC ef LDL-C, we compared, in an endemic area (Sao Tome island), two group s of patients children infected with Plasmodium falciparum (simple mal aria attack and cerebral malaria) with a control group of asymptomatic children. No correlation between lipid plasma levels and disease seve rity was found. Correlations between lipids and parasitemia or anemia were analysed. The mechanism of plasma lipid changes during attack are discussed.