STUDIES ON THE ENANTIOSELECTIVE DEPROTONATION OF 2,4-DIMETHYLBICYCLO[3.2.1]OCTAN-3-ONE

Authors
MAGEE DI SETIADJI S MARTIN RA
Citation
Di. Magee et al., STUDIES ON THE ENANTIOSELECTIVE DEPROTONATION OF 2,4-DIMETHYLBICYCLO[3.2.1]OCTAN-3-ONE, Tetrahedron : asymmetry, 6(3), 1995, pp. 639-642
Citations number
15
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
6
Issue
3
Year of publication
1995
Pages
639 - 642
Database
ISI
SICI code
0957-4166(1995)6:3<639:SOTEDO>2.0.ZU;2-5
Abstract
The desymmetrization of 2,4-dimethylbicyclo[3.2.1]octan-3-one by enant ioselective deprotonation with a variety of chiral amine bases has bee n studied. The enantioselectivities ranged from 5% for camphor derived amine 11 to 85% for Koga's base 13.