ENZYMATIC RESOLUTION OF 2-HYDROXY-4-PHENYLBUTANOIC ACID AND 2-HYDROXY-4-PHENYLBUTENOIC ACID

Authors
CHADHA A MANOHAR M
Citation
A. Chadha et M. Manohar, ENZYMATIC RESOLUTION OF 2-HYDROXY-4-PHENYLBUTANOIC ACID AND 2-HYDROXY-4-PHENYLBUTENOIC ACID, Tetrahedron : asymmetry, 6(3), 1995, pp. 651-652
Citations number
14
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
6
Issue
3
Year of publication
1995
Pages
651 - 652
Database
ISI
SICI code
0957-4166(1995)6:3<651:ERO2AA>2.0.ZU;2-O
Abstract
Racemic 2-hydroxy-4-phenylbutanoic acid and 2-hydroxy-4-phenyl-butenoi c acid have been resolved using a lipase. In each ease, the (R)-2-hydr oxy and the (S)-2-acetoxy acids were isolated with high enantiomeric e xcess and yield.