TOTAL SYNTHESIS OF (-COMPACTIN BY A DOUBLE MICHAEL PROTOCOL())

Authors
HAGIWARA H NAKANO T KONNO M UDA H
Citation
H. Hagiwara et al., TOTAL SYNTHESIS OF (-COMPACTIN BY A DOUBLE MICHAEL PROTOCOL()), Journal of the Chemical Society. Perkin transactions. I, (7), 1995, pp. 777-783
Citations number
25
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of the Chemical Society. Perkin transactions. I → ACNP
ISSN journal
0300922X
Issue
7
Year of publication
1995
Pages
777 - 783
Database
ISI
SICI code
0300-922X(1995):7<777:TSO(BA>2.0.ZU;2-F
Abstract
The total synthesis of (+)-compactin 1 has been achieved by employing a double Michael reaction of (R)-1-acetyl-3-(tert-butyldimethylsiloxy) cyclo 16 with methyl crotonate as the key reaction.