MULTIVARIATE CALIBRATION FOR PROTEIN, CHOLESTEROL AND TRIGLYCERIDES IN HUMAN PLASMA USING SHORT-WAVE NEAR-INFRARED SPECTROMETRY

Recent progress in spectroscopy and chemometrics have brought the reag entless analysis of blood substrates by near infrared spectroscopy int o clinical reach. Results for the in-vitro analysis of several blood s ubstrates in human blood plasma using multivariate calibration by part ial-least squares are presented for 125 hospital samples. Whereas the relative mean-squared prediction error for total protein (1.4%) using short wave NIR data is comparable with previous results using conventi onal NIR spectroscopy, the errors found for total cholesterol (6.5%) a nd triglycerides (13.8%) are nearly a factor of two worse for this stu dy.