ORAL PRESENTATION OF MINOCYCLINE-INDUCED BLACK BONE-DISEASE

Authors
ODELL EW HODGSON RP HASKELL R
Citation
Ew. Odell et al., ORAL PRESENTATION OF MINOCYCLINE-INDUCED BLACK BONE-DISEASE, Oral surgery, oral medicine, oral pathology, oral radiology and endodontics, 79(4), 1995, pp. 459-461
Citations number
22
Categorie Soggetti
Pathology,Surgery,"Dentistry,Oral Surgery & Medicine
Journal title
Oral surgery, oral medicine, oral pathology, oral radiology and endodontics → ACNP
ISSN journal
10792104
Volume
79
Issue
4
Year of publication
1995
Pages
459 - 461
Database
ISI
SICI code
1079-2104(1995)79:4<459:OPOMBB>2.0.ZU;2-5
Abstract
Minocycline hydrochloride is a semisynthetic tetracycline derivative u sed widely for the treatment of acne vulgaris. Among its side effects is the ability to pigment many tissues particularly thyroid, skin, too th, and bone. A case is presented in which long-term minocycline thera py (500g taken orally over 11 years) resulted in dark bone pigmentatio n (black bone disease) severe enough to be visible through the alveola r and palatal mucosa. No skin or tooth pigmentation was present.