EFFECTS OF INTRAVENOUS ANESTHETICS ON EXC ITATION, CONDUCTION, AND REFRACTORY PARAMETERS OF THE HEART - AN INVESTIGATION IN DOGS

Effects of Intravenous Anaesthetics on Excitation, Conduction, and Ref ractory Parameters of the Heart / An investigation in dogs Cardiac exc itation, conduction, and refractory parameters of the heart were inves tigated in 59 beagle dogs to obtain basic values under the influence o f the following 11 intravenous anaesthetic regimes using HIS-bundle el ectrography and programmed stimulation: 1. Alfentanil/midazolam/succin ylcholene; 2. Alfentanil/midazolam/succinylcholine/atropine; 3. fentan yl/midazolam/pancuronium bromide; 4. fentanyl-droperidol/chloralose/ur ethane; 5. ketamine/xylazine; 6. ketamine/xylazine/atropine; 7. propio nylpromazine/pentobarbital; 8. propionylpromazine/levomethadon; 9. pro pofol; 10. propofol/alfentanil; 11. Tiletamine-zolazepam. It could be shown, that some intravenous anaesthetics under laboratory conditions have a strong influence on the observed cardiac parameters that must b e considered in experiments with other substances or in cardiovascular results.