DISTRIBUTION OF HLA ANTIGENS IN INDIAN GURKHA POPULATION

Authors
CHAUDHURI TK MANDAL TK SEN TK TANEJA V
Citation
Tk. Chaudhuri et al., DISTRIBUTION OF HLA ANTIGENS IN INDIAN GURKHA POPULATION, INDIAN JOURNAL OF MEDICAL RESEARCH, 101, 1995, pp. 170-172
Citations number
9
Categorie Soggetti
Medicine, General & Internal",Immunology
Journal title
INDIAN JOURNAL OF MEDICAL RESEARCH → ACNP
ISSN journal
09715916
Volume
101
Year of publication
1995
Pages
170 - 172
Database
ISI
SICI code
0971-5916(1995)101:<170:DOHAII>2.0.ZU;2-5
Abstract
Fifty unrelated Indian Gurkha of Nepalese origin were studied to analy se the HLA antigen profile and their relation with other populations. Halotype B35-Cw4 occurred with highest incidence and significant posit ive linkage disequilibrium in Gurkhas. Haplotype A10-B8 which occurs w ith the highest frequency in north Indians was also observed to occur with significant positive linkage in Gurkhas, HLA profile of Gurkhas t hus may be the result of long-term isolation and genetic drift.