THE EFFECT OF HYPERVENTILATION ON MOTOR CORTICAL INHIBITION IN HUMANS- A STUDY OF THE ELECTROMYOGRAPHIC SILENT PERIOD EVOKED BY TRANSCRANIAL BRAIN-STIMULATION
A. Priori et al., THE EFFECT OF HYPERVENTILATION ON MOTOR CORTICAL INHIBITION IN HUMANS- A STUDY OF THE ELECTROMYOGRAPHIC SILENT PERIOD EVOKED BY TRANSCRANIAL BRAIN-STIMULATION, ELECTROMYOGRAPHY AND MOTOR CONTROL-ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY, 97(1), 1995, pp. 69-72
We studied the effects of hyperventilation under control of the end-ti
dal PCO2, on the electromyographic silent period evoked by transcrania
l magnetic brain stimulation and by peripheral nerve stimulation. We a
lso studied the effects of hyperventilation on the threshold, latency
and amplitude of motor potentials. Hyperventilation significantly redu
ced the duration of the cortical silent period, but did not affect the
length of the peripheral silent period. Neither did it alter the late
ncy, amplitude or threshold of the motor potentials. These findings su
ggest that hyperventilation selectively depresses motor cortical inhib
ition in humans.