F. Almqvist et T. Frejd, OPTICALLY-ACTIVE BICYCLO[2.2.2]OCTANE DERIVATIVES - SYNTHESIS OF (1S,4R,6R)-6-HYDROXYBICYCLO[2.2.2]OCTAN-2-ONE FROM ITS ENANTIOMER, Tetrahedron : asymmetry, 6(4), 1995, pp. 957-960
(1S, 4R, 6R)-6-Hydroxybicyclo[2.2.2]octan-2-one, (+)-1, is synthesized
from its enantiomer in 6 steps using a combination of orthogonal prot
ecting groups and red-ox chemistry.