SYNTHESIS OF GEM-BISPHOSPHONIC CONJUGATES OF CORTISONE DERIVATIVES

Authors
GUERVENOU J STURTZ G
Citation
J. Guervenou et G. Sturtz, SYNTHESIS OF GEM-BISPHOSPHONIC CONJUGATES OF CORTISONE DERIVATIVES, Phosphorus, sulfur and silicon and the related elements, 88(1-4), 1994, pp. 1-13
Citations number
36
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Phosphorus, sulfur and silicon and the related elements → ACNP
ISSN journal
10426507
Volume
88
Issue
1-4
Year of publication
1994
Pages
1 - 13
Database
ISI
SICI code
1042-6507(1994)88:1-4<1:SOGCOC>2.0.ZU;2-0
Abstract
Some gem-bisphosphonic cortico-steroid conjugates are prepared by este rification between gem-bisphosphonate carboxylic acids and steroid pri mary alcohols. These original products take place in a biological stud y about a delivery-targeting concept of active constituents in bone th erapy, with the assistance of gem-bisphosphonic building-blocs.