STUDIES ON YLPURIMIDINYLTHIO]-BETA-(4-PHENYLBENZOYL)PROPIONIC ACID AND THE BIOLOGICAL-ACTIVITY OF SOME PRODUCTS

Authors
ARIEF MMH ESSAWY SA WASFY AAF NASSAR SA HASHISH AA
Citation
Mmh. Arief et al., STUDIES ON YLPURIMIDINYLTHIO]-BETA-(4-PHENYLBENZOYL)PROPIONIC ACID AND THE BIOLOGICAL-ACTIVITY OF SOME PRODUCTS, Phosphorus, sulfur and silicon and the related elements, 91(1-4), 1994, pp. 1-7
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Phosphorus, sulfur and silicon and the related elements → ACNP
ISSN journal
10426507
Volume
91
Issue
1-4
Year of publication
1994
Pages
1 - 7
Database
ISI
SICI code
1042-6507(1994)91:1-4<1:SOYAA>2.0.ZU;2-8
Abstract
beta-(4-phenylbenzoyl)acrylic acid I reacted with ethoxynaphthalenyl)- 4-phenylpyrimidine-2(1H)thione to furnish (2'-methoxynaphthalenyl)-4-p henylpyrimidinylthio]- beta-(4-phenylbenzoyl)propionic acid II. Dehydr ation of acid II aforded furanone derivative III. The behaviour of III towards hydrazine hydrate, hydroxylamine hydrochloride, primary amine s, aromatic hydrocarbons (under Friedel-Crafts conditions) and carbon nucleophiles (under Grignard conditions) has been investigated.