In the literature 20 cases of fat embolism syndrome (FES) after total
knee replacement (TKR) are reported; 16 cases had cemented hinged TKR
and 4 resurfacing TKR. Initially, it was believed that the bone cement
was responsible for the FES. Since then, however, Fahmy et al. have p
ublished extraordinary data, demonstrating the causal relationship bet
ween increased intramedullary pressure (IMP) during the insertion of t
he intramedullary rod (IR) and cardiorespiratory deterioration. The in
dustry responded by developing a fluted IR, disregarding the overdrill
ing in the distal femur required by Fahmy. In the first part of this p
aper clinically manifest FES cases after resurfacing TKR are reported.
In the second part of the study the conventional surgical technique i
s compared with a modified technique, which focuses on a reduction of
bone-marrow release into the circulation. In the conventional and the
modified group, IRs with and without; flutes were compared. It was sho
wn that only the opening of the intramedullary canal and insertion of
the IR generated relevant IMP peaks during implantation of resurfacing
TKR. When compared with the conventional surgical technique, the modi
fied technique revealed significantly lower IMPs, and in neither group
was a difference demonstrated between the IR with or without flutes.
In 4 patients (2 conventional, 2 modified) transesophageal echocardiog
raphy (TEE) was performed for detection of bone-marrow release into th
e circulation. In the two patients operated on conventionally, TEE sho
wed a markedly higher bone-marrow release than in the patients with mo
dified operations. In conclusion, we recommend the presented modified
surgical technique in order to reduce bone-marrow release into the cir
culation.