Gr. Pettit et al., THE DOLASTATINS .25. CONFORMATIONAL ISOMERISM OF N-BENZYLOXYCARBONYL-N-METHYLISOLEUCINOL AND RELATED SUBSTANCES, Perkin transactions. 2, (5), 1995, pp. 919-921
Conformational isomerism in a selection of N-Z-N-methylisoleucine deri
vatives was detected and investigated using variable temperature NMR s
pectroscopy. Thermodynamic values for the restricted rotation of confo
rmational isomers were derived.