The ability to study regional cerebral blood flow (rCBF) is available
in many institutions, especially with the spread of multi-headed gamma
cameras. The use of this technique in paediatrics requires special at
tention to detail in the manner of data acquisition and handling the c
hild. The interpretation of the rCBF study in a child requires knowled
ge of normal brain maturation. The major clinical use in paediatrics i
s epilepsy because of the advances in surgery and the frequency of com
plex partial seizures. Other indications in paediatric neurology inclu
de brain death, acute neurological loss including stroke, language dis
orders, cerebral palsy, hypertension due to renovascular disease, trau
matic brain injury and migraine. There are paediatric psychological co
nditions in which rCBF assessment has been undertaken, including anore
xia nervosa, autism, Gilles de la Tourette Syndrome (GTS) and attentio
n deficit disorder-hyperactivity (ADHD). This article attempts to revi
ew all aspects of rCBF studies in paediatrics.