ALL-METAL COLLECTION SYSTEM FOR PREPARATIVE-SCALE GAS-CHROMATOGRAPHY - PURIFICATION OF LOW-BOILING-POINT COMPOUNDS

We describe a purification system based on a commercial preparative-sc ale gas chromatograph with a custom-designed condenser, collector, and fraction handling system. In our fraction collector design, all the w etted surfaces were either 316 stainless-steel or nickel. The collecto rs and the integrated gas-handling manifold were designed to be used d own to liquid nitrogen temperature and up to 7 MPa of pressure to acco mmodate low-boiling-point compounds, such as refrigerants. The design, operation, and performance of this apparatus are presented.