MEASUREMENT OF THE NASAL MUCOCILIARITY CL EARANCE BY A MODIFIED SACCHARIN METHOD

To measure the complex nasal clearance we propose to perform our varia tion of the Andersen saccharin method as a saccharin liquid test (SLT) . The application of 3 molar aqueous sodium saccharin solutions with a Wiretrol capillary on the concha nasalis inferior or media allows sim ple handling, exact dosage, minimal nasal irritation and an increase i n reproducibility. Application of 1 microlitre is sufficient to carry out the test. In the present study 48 healthy volunteers without any n ose disease or history of sinusitis showed a saccharin transport rate of 10.4 (SD 4.2) minutes.