NEW FLUORINATED O-ARYL LACTIC ACIDS - USE AS CHIRAL DERIVATIZING AGENTS (CDAS) AND DETERMINATION OF THEIR ENANTIOMERIC PURITY WITH ACHIRAL DIOLS

Authors
HEUMANN A LOUTFI A ORTIZ B
Citation
A. Heumann et al., NEW FLUORINATED O-ARYL LACTIC ACIDS - USE AS CHIRAL DERIVATIZING AGENTS (CDAS) AND DETERMINATION OF THEIR ENANTIOMERIC PURITY WITH ACHIRAL DIOLS, Tetrahedron : asymmetry, 6(5), 1995, pp. 1073-1076
Citations number
20
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
6
Issue
5
Year of publication
1995
Pages
1073 - 1076
Database
ISI
SICI code
0957-4166(1995)6:5<1073:NFOLA->2.0.ZU;2-U
Abstract
The modification of the aromatic part of fluorinated O-aryl lactic aci ds allows the improvement of the fluorine NMR delta Delta values in di astereomeric esters, but also the observation of other nuclei such as Hg (delta Delta > 6 ppm). The enantiomeric purity of chiral acids has been determined through the dl- and meso compounds formed from achiral diols.