A NEW APPROACH TO FUNCTIONALIZED CYCLOBUTANES - STEREOSELECTIVE SYNTHESIS OF THE ENANTIOMERS OF GRANDISOL AND FRAGANOL

Authors
MARTIN T RODRIGUEZ CM MARTIN VS
Citation
T. Martin et al., A NEW APPROACH TO FUNCTIONALIZED CYCLOBUTANES - STEREOSELECTIVE SYNTHESIS OF THE ENANTIOMERS OF GRANDISOL AND FRAGANOL, Tetrahedron : asymmetry, 6(5), 1995, pp. 1151-1164
Citations number
19
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
6
Issue
5
Year of publication
1995
Pages
1151 - 1164
Database
ISI
SICI code
0957-4166(1995)6:5<1151:ANATFC>2.0.ZU;2-9
Abstract
Enantiomerically enriched (+)-grandisol and (+)-fraganol were synthesi zed using as the key step a new stereoselective synthesis of cyclobuta nes fused to gamma-lactones by a stereochemically-controlled intramole cular alkylation of alpha-benzenesulfonyl-gamma-lactones. This method provides a way to synthesize the enantiomers in a straightforward mann er.