SYNTHESIS OF A NONASACCHARIDE WITH 2 LEWIS-X TRISACCHARIDES ANCHORED ONTO A BRANCHED TRIMANNOSIDE

Authors
ZHANG YM BRODZKY A SINAY P SAINTMARCOUX G PERLY B
Citation
Ym. Zhang et al., SYNTHESIS OF A NONASACCHARIDE WITH 2 LEWIS-X TRISACCHARIDES ANCHORED ONTO A BRANCHED TRIMANNOSIDE, Tetrahedron : asymmetry, 6(5), 1995, pp. 1195-1216
Citations number
51
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
6
Issue
5
Year of publication
1995
Pages
1195 - 1216
Database
ISI
SICI code
0957-4166(1995)6:5<1195:SOANW2>2.0.ZU;2-3
Abstract
Double condensation of phenyl enzyl-2-O-[6-O-benzyl-2-deoxy-2-phthalim ido-4-O-(2 zyl-alpha-L-fucopyranosyl)-beta-D-glucopyranosyl]- 1-thio-a lpha-D-mannopyranoside 31 with methyl 2,4-di-O-benzyl-beta-D-mannopyra noside 35, in the presence of N-iodosuccinimide/trifluoromethane-sulfo nic acid, gave the protected nonasaccharide 36 in 60% yield. Conventio nal deprotection gave the nonasaccharide 1, in which two Lewis x trisa ccharides are anchored onto a branched trimannoside.