ERYTHROPOIETIN - PHYSICOCHEMICAL-ANALYSIS AND BIOCHEMICAL-ANALYSIS

A hormone, erythropoietin, mainly produced in adult kidneys and fetal livers, acts on bone marrow erythroid progenitor cells to regulate the production of erythrocyte in mammals. As a result, the oxygen carryin g capacity of blood increases and the increased oxygen supply raises t he cardiac function and physiological working capacity. Erythropoietin is possibly misused by athletes in sports for the purpose of improvin g performance. Presently there is no discernible and specific method t o identify erythropoietin administration for doping control. To addres s this practical problem, this paper presents a summary of the applica tions of analytical biotechnology, especially the structural character ization of erythropoietin.