MUTAGENIC ACTIVITY OF THE GANGES WATER WITH SPECIAL REFERENCE TO THE PESTICIDE POLLUTION IN THE RIVER BETWEEN KACHLA TO KANNAUJ (UP), INDIA

Water samples from Ganga river were collected from 3 different locatio ns viz. Kachla, Fatehgarh and Kannauj (U.P.). High performance liquid chromatography analysis of samples by liquid-liquid extraction procedu re showed the presence of some pesticides like DDT, alpha-BHC, aldrin, dieldrin etc. DDT, alpha-BHC, DDD, aldrin and dieldrin were present a t concentration ranges of 3.33-5.33 ppb, 1.73-3.01 ppb, 0.88-2.41 ppb, 1.17-2.81 ppb and 0.49-4.11 ppb, respectively. The organophosphorus p esticides like dimethoate and methyl parathion were also detected at t he concentration levels of 0.41-0.56 ppb and 0.16-0.50 ppb, respective ly. The organic substances in the test samples were extracted by XAD-r esin and liquid-liquid extraction procedures, and the extracts were as sayed for mutagenic potential by the Ames Salmonella/microsome test. T he test samples exhibited a remarkable degree of mutagenicity with TA9 8, TA100 and TA97a strains with the probable role of contaminating pes ticides in the river water.