Ms. Keshavan et al., A COMPARISON OF STEREOLOGY AND SEGMENTATION TECHNIQUES FOR VOLUMETRICMEASUREMENTS OF LATERAL VENTRICLES IN MAGNETIC-RESONANCE-IMAGING, PSYCHIATRY RESEARCH-NEUROIMAGING, 61(1), 1995, pp. 53-60
Lateral ventricular volumes were measured on magnetic resonance imagin
g (MRI) scans by independent raters in 18 subjects (11 psychotic patie
nts and 7 healthy control subjects) with two different approaches: a p
oint-counting stereological (PCS) technique and a computerized techniq
ue based on segmentation algorithms. The correlation between the two t
echniques was very high (r = 0.96), and phantom studies showed good va
lidity for both approaches. These findings and the technical simplicit
y of the PCS technique support its potential use for MRI morphometric
measurements.