A. Semenzato et al., HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC DETERMINATION OF IONIC COMPOUNDS IN COSMETIC EMULSIONS - APPLICATION TO MAGNESIUM ASCORBYL PHOSPHATE, Journal of chromatography, 705(2), 1995, pp. 385-389
A rapid, reliable method based on reversed-phase high performance liqu
id chromatography for the qualitative and quantitative determination o
f magnesium ascorbyl phosphate (VC-PMG) in both standard solutions and
cosmetic products is reported. The procedure, based on an aminic stat
ionary phase and acetonitrile-0.3 M phosphate buffer (pH 4) (40:60) as
the mobile phase, allows the determination of VC-PMG in cosmetic samp
les after dilution with a tetrahydrofuran-0.3 M phosphate buffer (pH 4
) (3:7) solvent mixture.