Sebaceous glands on the vermilion border of the lips and the oral muco
sa are common in adults. Only pathologic sebaceous glands visible thro
ugh the epithelium should be regarded as Fordyce's granules. The incid
ence of Fordyce's granules increases from childhood to adulthood, and
is slightly higher in men. The most prevalent sites are the vermilion
border of the lips and the buccal mucosa. Fordyce's granules usually h
ave the same histological features as cutaneous sebaceous glands. Path
ologic alterations are rare. There is no significant correlation betwe
en Fordyce's granules and systemic diseases.