H. Leturkonirsch et al., PREMATURE OVARIAN FAILURE AND STRESS, Comptes rendus de l'Academie des sciences. Serie 3, Sciences de la vie, 318(6), 1995, pp. 691-698
By acting on the neuroendocrine system during the stress response, lif
e events may greatly affect homeostasis and favor the appearance of di
sease. Here, we describe a relationship between stressful life events
and premature ovarian failure. From a mechanic point of view, we sugge
st an autoimmune origin for such premature ovarian failure on the basi
s of the role of cytokines in folliculogenesis and of their increased
production during stressful life events.