SERUM ADENOSINE-DEAMINASE, 5'-NUCLEOTIDASE AND ALKALINE-PHOSPHATASE IN BREAST-CANCER PATIENTS

Serum levels of adenosine deaminase (ADA), 5-nucleotidase (5'-NT) and alkaline phosphatase (AEP) were studied in 25 patients of carcinoma br east and 25 normal subjects, Adenosine deaminase was found to be the b etter probable parameter for the detection of cancer and to assess the development of various stages of cancer whereas 5'-nucleotidase had o nly diagnostic significance. Serum alkaline Phosphatase levels were im portant for assessing the spread of cancer at secondary sites. After m astectomy a significant decrease was found in the levels of serum ADA and 5'-NT whereas no variations were found in case of serum ALP.