OXIDATION OF METHYL P-TOLYL SULFIDE WITH BAKERS-YEAST - PREPARATION OF A SYNTHON OF THE MEVINIC ACID-TYPE HYPOCHOLESTEMIC AGENTS

Authors
BEECHER J BRACKENRIDGE I ROBERTS SM TANG J WILLETTS AJ
Citation
J. Beecher et al., OXIDATION OF METHYL P-TOLYL SULFIDE WITH BAKERS-YEAST - PREPARATION OF A SYNTHON OF THE MEVINIC ACID-TYPE HYPOCHOLESTEMIC AGENTS, Journal of the Chemical Society. Perkin transactions. I, (13), 1995, pp. 1641-1643
Citations number
29
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of the Chemical Society. Perkin transactions. I → ACNP
ISSN journal
0300922X
Issue
13
Year of publication
1995
Pages
1641 - 1643
Database
ISI
SICI code
0300-922X(1995):13<1641:OOMPSW>2.0.ZU;2-T
Abstract
Bakers' yeast oxidized methyl p-tolyl sulfide to produce the R-sulfoxi de 1 in good yield and high enantiomeric excess; the sulfoxide 1 was u sed to prepare(4R,6S)- thylsilyloxy-6-hydroxy-methyltetrahydropyran-2- one 15.