CUPROUS BROMIDE-PROMOTED CYCLIZATION OF KETENE N,S-ACETALS WITH PROP-2-YNYL BROMIDE - SYNTHESIS OF REGIOSPECIFICALLY SUBSTITUTED AND ANNELATED 3-ACYL(OR NITRO)-5-METHYL PYRROLES

Authors
GUPTA AK REDDY KR ILA H JUNJAPPA H
Citation
Ak. Gupta et al., CUPROUS BROMIDE-PROMOTED CYCLIZATION OF KETENE N,S-ACETALS WITH PROP-2-YNYL BROMIDE - SYNTHESIS OF REGIOSPECIFICALLY SUBSTITUTED AND ANNELATED 3-ACYL(OR NITRO)-5-METHYL PYRROLES, Journal of the Chemical Society. Perkin transactions. I, (13), 1995, pp. 1725-1727
Citations number
20
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of the Chemical Society. Perkin transactions. I → ACNP
ISSN journal
0300922X
Issue
13
Year of publication
1995
Pages
1725 - 1727
Database
ISI
SICI code
0300-922X(1995):13<1725:CBCOKN>2.0.ZU;2-I
Abstract
Acyclic 10a-h and cyclic 14a-b acyl and nitroketene 12a-b N,S-acetals undergo facile cuprous bromide induced cyclization with prop-2-ynyl br omide to afford 1-substituted-3-acyl(or nitro)-5-methyl-2-(methylsulfa nyl)pyrroles 11a-h and 13a-b and the corresponding annealated analogue s 15a-b in good yields.