MEDIUM-SIZED CYCLOPHANES .35. SYNTHESIS AND ELECTROPHILIC AROMATIC-SUBSTITUTION OF 8,14,22,28-TETRASUBSTITUTED [2.0.2.0]METACYCLOPHANES

Authors
YAMATO T DOAMEKPOR LK HASEGAWA KI FURUKAWA T TASHIRO M
Citation
T. Yamato et al., MEDIUM-SIZED CYCLOPHANES .35. SYNTHESIS AND ELECTROPHILIC AROMATIC-SUBSTITUTION OF 8,14,22,28-TETRASUBSTITUTED [2.0.2.0]METACYCLOPHANES, Journal of chemical research. Synopses, (5), 1995, pp. 168-169
Citations number
32
Categorie Soggetti
Chemistry
Journal title
Journal of chemical research. Synopses → ACNP
ISSN journal
03082342
Issue
5
Year of publication
1995
Pages
168 - 169
Database
ISI
SICI code
0308-2342(1995):5<168:MC.SAE>2.0.ZU;2-S
Abstract
Friedel-Crafts acetylation of anti-8,14,22,28-tetramethyl[2.0.2.0]meta cyclophane (anti-13a) occurs selectively at the 5,11,19,25-positions t o afford the tetraacetyl derivative anti-18a in 67% yield, whereas in other electrophilic substitutions this selectivity is not observed.