We report a case of iliac stent infection. Nine days after a 24-hour i
nfusion of urokinase and right iliac artery stent deployment, the pati
ent had fever, in addition to severe groin pain and petechiae isolated
to the stented limb. The hospital course was complicated by sepsis, a
dult respiratory distress syndrome, liver dysfunction, and renal insuf
ficiency. Stent removal and iliac/femoral artery resection, as well as
an above-knee amputation, were life-saving. Arterial and stent cultur
es grew Staphylococcus aureus. Stent infection with arterial necrosis
is a devastating, rare endovascular complication. Given its potential
seriousness, we would recommend the use of prophylactic antibiotics be
fore stent deployment.