The hypothesis that the evaluation of one's health as poor is associat
ed with mortality, independent of the results of a standardized medica
l examination, was tested in the Kaunas-Rotterdam Follow-Up Study. In
this study two cohorts, one consisting of 2452 Lithuanian males and on
e of 3365 Dutch males, aged 45-60, were screened for cardiovascular ri
sk factors in 1973, using identical protocols, and were followed for a
bout ten years. Self-rated health was assessed by two direct questions
: 'How would you assess your own health?' and 'What do you think of yo
ur own health compared to that of other men of your age?' as well as b
y a Semantic Differential Test of 'My Health'. In both cohorts a negat
ive evaluation of one's health was associated with mortality, controll
ing for past or present heart disease, cardiovascular risk factors, pa
rental life span, socio-economic and marital status. Especially the da
ta with regard to the comparative question indicate that self-rated he
alth is associated with mortality in men living in two different socio
-cultural systems. The data suggest that a weak sense of mastery may e
xplain the association between health perception and mortality.