Atrial tachycardias are frequently unresponsive to medical therapy. Hi
s bundle ablation has been proposed as a palliative treatment to treat
symptoms and prevent development of tachycardia-mediated cardiomyopat
hy. Experience with catheter ablation directed at the atrial origin of
the tachycardia remains limited. We reviewed the initial success rate
and long-term follow-up of radiofrequency ablation of atrial tachycar
dias. Thirty-six patients underwent electrophysiologic study and radio
frequency ablation of atrial tachycardias, excluding atrial flutter. T
he suspected mechanism of the clinical arrhythmia was automatic in 16
patients, intraatrial reentrant in 15, sinoatrial reentrant in 3, and
unknown in 2. One or two ablation catheters with a 4 mm distal electro
de were used to find (1) the earliest local atrial activation time com
pared to P-wave onset in the bipolar recording mode and (2) a QS patte
rn in the unipolar mode. When two ablation catheters were used, an enc
ircling approach was taken. Pace-mapping during sinus rhythm and entra
inment techniques were occasionally used for mapping. Tachycardia rose
from the right atrium in 33 of 36 patients and from the left atrium i
n the remaining three. Three patients showed multiple foci during the
procedure. Successful ablation was obtained in 31 (86%) of 36 patients
, with a median of two radiofrequency applications (range 1 to 32) at
10 to 50 W for 10 to 60 seconds. Failure occurred in 5 patients (inclu
ding the 3 patients with multiple atrial foci). Late follow-up (18 +/-
15 months) showed recurrence of atrial tachycardia in 2 patients, eac
h of whom underwent a successful second ablation. Emergence of another
atrial tachycardia was noted in 2 other patients, and an uncommon atr
ial flutter was noted in 1 patient with repaired atrial septal defect.
No late sinus or atrioventricular nodal dysfunction were observed. In
conclusion, radiofrequency catheter ablation is a safe and reasonable
alternative for atrial tachycardias that do not respond to drugs. How
ever, as previously suggested by the surgical experience, the success
rate of ablation appears less satisfactory in patients with multiple s
ites of origin of ectopic atrial tachycardia.