Dermatomyositis, polymyositis and inclusion body myositis are all rare
inflammatory immunogenic muscle diseases. Dermatomyositis usually man
ifests in an acute form, polymyositis subacutely, and inclusion body m
yositis as a chronic condition. They share the cardinal clinical sympt
oms progressive paresis and atrophy. Muscle pain is not obligatory and
is observed most often in acute stages. Technical diagnosis includes
biochemical analysis, electromyography, magnetic resonance imaging ii
necessary and, finally, muscle biopsy. Dermatomyositis and polymyositi
s are predominantly treated with glucocorticoids and azathioprine. As
yet there is no known effective treatment for inclusion body myositis.
Differential diagnosis for myalgia covers a wide spectrum. Inflammato
ry muscle disease should always be suspected in cases of mesenchymal m
uscle pain in combination with paresis. However, there are also pain-f
ree forms of myositis.