A FACILE AND EFFICIENT ROUTE TO THE BICYCLO[3.2.1]OCTANE SYSTEM - APPLICATION TO THE ENANTIOSELECTIVE APPROACH TO CYCLOPENTANOIDS

Authors
KOSUGI H SUGIURA J KATO M
Citation
H. Kosugi et al., A FACILE AND EFFICIENT ROUTE TO THE BICYCLO[3.2.1]OCTANE SYSTEM - APPLICATION TO THE ENANTIOSELECTIVE APPROACH TO CYCLOPENTANOIDS, Chemical communications, (24), 1996, pp. 2743-2744
Citations number
19
Categorie Soggetti
Chemistry
Journal title
Chemical communications → ACNP
ISSN journal
13597345
Issue
24
Year of publication
1996
Pages
2743 - 2744
Database
ISI
SICI code
1359-7345(1996):24<2743:AFAERT>2.0.ZU;2-W
Abstract
The reaction of (1,2-epoxy-1-methyl-ethyl)-5--methylcyclohex-1-ene 8 w ith BF3 . Et(2)O provides, in one chemical operation, )-7-acetoxy-4,6- dimethylbicyclo[3.2.1]octan-2-ones 9a,b which are then transformed to -methyl-3-[(R)-1-methyl-3-oxobutyl]-cyclopentanone 16 with the same ab solute configuration as that of the steroid D ring.