Ar. Zlotta et al., TRANSURETHRAL NEEDLE ABLATION OF THE PROSTATE - CLINICAL-EXPERIENCE IN PATIENTS IN URINARY ACUTE RETENTION, British Journal of Urology, 77(3), 1996, pp. 391-397
Objective To evaluate the clinical outcome of patients in urinary rete
ntion due to benign prostatic enlargement (BPE) treated using transure
thral needle ablation (TUNA), an outpatient procedure requiring only l
ocal intra-urethral anaesthesia and intravenous sedoanalgesia. Patient
s and methods The TUNA technique was used in 38 patients in acute rete
ntion due to BPE, 34 of whom were a poor surgical risk. A special cyst
oscopic catheter device delivered low-level radiofrequency (RF) energy
interstitially to a localized area of the prostate, producing necroti
c lesions within the prostatic parenchyma. After treatment, all men we
re evaluated using urinary flow rates, residual urine volume, the Inte
rnational Prostate Symptom Score and quality of life score at 1, 3 and
6 months. Results The mean prostate size was 43.1 g (range 18-90). To
lerance of the procedure when using topical anaesthetic and intravenou
s sedation was excellent, Of the 38 patients treated using TUNA, 30 (7
9%) resumed voiding within a mean of 8.7 days (range 2-27). After 6 mo
nths, the sustained mean peak flow rate was 10.4+/-3.4 mL/s and the me
an residual volume was 76+/-45 mL. Five of the patients who did not re
sume voiding after TUNA underwent retropubic prostatectomy and one pat
ient underwent TURF, The mean prostate size in these patients was 55.7
g. Failure to void was associated with the treatment of too few areas
of the prostate for its volume. Conclusion This study demonstrated th
at TUNA is highly effective in relieving patients in urinary retention
due to BPE and seems particularly suitable for treating patients who
are at greater risk during surgery.