Purpose: We evaluated risk factors for the development of bladder tumo
rs in spinal cord injury patients. Materials and Methods: A retrospect
ive review was done of all bladder tumors at 1 institution with matche
d controls for 7 years. Results: We identified 17 malignant and 2 beni
gn tumors. Indwelling bladder catheters and a history of bladder stone
s were statistically significant risk factors. Four patients with nega
tive biopsies underwent repeat biopsy due to suspicious cytology and c
ancer was found. Conclusions: An indwelling urinary catheter and a his
tory of bladder stones are statistically significant risk factors. Cyt
ology and biopsy are complementary in the evaluation of urothelial mal
ignancy in this population. A high index of suspicion and thorough eva
luation are needed in spinal cord injury patients.