HCV RNA DETECTION IN PAROTID-GLAND BIOPSY IN A PATIENT WITH CHRONIC HEPATITIS-C VIRUS LIVER-DISEASE

Authors
BIASI D COLOMBARI R ACHILLE A CARLETTO A CARAMASHI P CORROCHER R BAMBARA LM
Citation
D. Biasi et al., HCV RNA DETECTION IN PAROTID-GLAND BIOPSY IN A PATIENT WITH CHRONIC HEPATITIS-C VIRUS LIVER-DISEASE, Acta Gastro-Enterologica Belgica, 58(5-6), 1995, pp. 465-469
Citations number
14
Categorie Soggetti
Gastroenterology & Hepatology
Journal title
Acta Gastro-Enterologica Belgica → ACNP
ISSN journal
00015644
Volume
58
Issue
5-6
Year of publication
1995
Pages
465 - 469
Database
ISI
SICI code
0001-5644(1995)58:5-6<465:HRDIPB>2.0.ZU;2-P
Abstract
We report a case of a 75-year-old woman admitted to our Unit for chron ic sialadenitis, characterized by histologic evidence of B and T lymph ocyte infiltrate; laboratory and histologic tests revealed chronic hep atitis C, without autoimmune markers. We found hepatitis C virus (HCV) RNA in liver, in parotid gland, in saliva and in peripheral blood mon onuclear cells, but not in serum. HCV RNA was detected by PCR techniqu e. To our knowledge this is the first case of detection of HCV RNA in parotid gland. This finding raises the question about the relationship between sialadenitis and viral HCV infection.