PURPOSE: To determine if serous retinal detachment may occur in a case
of Epstein-Barr virus-associated T-cell lymphoma. METHODS: We examine
d a 51-year-old man who had recent. loss of vision and poor general he
alth. RESULTS: Ocular involvement consisted of bilateral serous retina
l detachment: and choroidal infiltrates. The diagnosis of lymphoma was
made by liver biopsy. The course of the disease was fulminant. Postmo
rtem histologic examination disclosed a massive infiltration of the ch
oroid and hematopoietic organs by pleomorphic large T cells. Epstein-B
arr virus was detected by in situ hybridization. CONCLUSION: Ocular in
volvement, including choroidal infiltrates and serous retinal detachme
nt, may occur in Epstein-Barr virus-associated T-cell lymphoma.