SEROEPIDEMIOLOGICAL AND LEISHMANIN SKIN-TEST SURVEYS OF VISCERAL LEISHMANIASIS IN SOUTH AND SOUTHWEST ETHIOPIA

Sero-epidemiological and leishmanin skin test surveys of visceral leis hmaniasis were carried out in eight localities of South and Southwest Ethiopia between the July 1989 and June 1992. A total number of 4870 s ubjects comprising semi-pastoral nomads, peasants and farm labourers w ere included in the study. Areas of high and low leishmanin skin test positivity were identified, with rates varying from 1.0 - 80.5%. An en zyme-linked immunosorbent assay was used to determine prevalence of an tileishmanial antibodies. The rates varied from 1.8% to 27.8%. Age and sex related serological and leishmanin skin test profiles are describ ed. Correlation analysis of serological and leishmanin skin test was m ade for data in each locality. The relationships between seroprevalenc e, leishmanin skin test rates and prevalence of active visceral leishm aniasis and the implications on degrees of endemicity and patterns of transmission are discussed.