MOLECULAR DETERMINANTS OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-I PHENOTYPE VARIABILITY

Authors
FOUCHIER RAM SCHUITEMAKER H
Citation
Ram. Fouchier et H. Schuitemaker, MOLECULAR DETERMINANTS OF HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-I PHENOTYPE VARIABILITY, European journal of clinical investigation, 26(3), 1996, pp. 175-185
Citations number
152
Categorie Soggetti
Medicine, Research & Experimental","Medicine, General & Internal
Journal title
European journal of clinical investigation → ACNP
ISSN journal
00142972
Volume
26
Issue
3
Year of publication
1996
Pages
175 - 185
Database
ISI
SICI code
0014-2972(1996)26:3<175:MDOHTP>2.0.ZU;2-A
Abstract
The clinical course of HIV-1-infected individuals can be highly variab le. Progression to AIDS can occur within 1 year after infection but sy mptom-free infection for more than 15 years has also been reported. Th is variation can either be determined by host factors, the biological variability of the virus or both. Here the molecular determinants and clinical relevance of HIV-1 biological phenotype variability are revie wed.