Aj. Treloar et al., PUPILLARY RESPONSE TO TOPICAL TROPICAMIDE AS A MARKER FOR ALZHEIMERS-DISEASE, British journal of clinical pharmacology, 41(3), 1996, pp. 256-257
The mydriatic response to eyedrops of the anticholinergic drug tropica
mide at very low concentration (0.01%) was studied in subjects with Al
zheimer's disease (AD, n=10) and multi-infarct dementia (MID, n=10). T
here was no significant difference in pupillary response between the t
wo groups. The test is unlikely to be useful in differentiating differ
ent types of dementia.