J. Brocas et C. Fromageot, THERMOREGULATION IN HOMEOTHERMS - CENTRAL TEMPERATURE RESULTS FROM OPTIMIZATION OF ENERGY TRANSFERS, Biological cybernetics, 74(3), 1996, pp. 225-234
In contrast to the classical homeostatic concept of the constancy of t
he central temperature, this study proposes an original model of therm
oregulation based on the optimization of energy transfers. Exchange of
the energy consumed or produced by the cell between the cell and the
external medium has an associated energy cost. The different variables
of the internal medium - flows, pressures, concentrations and also te
mperatures, since heat is but a particular form of energy - are contin
uously set at optimal values such that this cost is always minimal for
the prevailing constraints with which the organism is faced. The prop
osed thermoregulatory model accounts for the physiological spatial and
temporal variability of the body's temperatures. The predictive curve
s suggest a new approach to experimental studies concerned with therma
l regulation and throw new light on their results.