M. Yasuda et al., EFFECTS OF 6-HYDROXYDOPAMINE ON THE ANTIBODY-RESPONSE TO THE HAPTEN DINITROPHENYL IN THE CHICKEN, Journal of veterinary medical science, 57(6), 1995, pp. 1073-1075
Antibody responses to the hapten dinitrophenyl (DNP) and the concentra
tion of catecholamine in chickens received a single injection of 6-Hyd
roxydopamine (6-OHDA) into the chorioallantoic cavity at the embryonal
stage were evaluated. A significantly enhanced anti-DNP IgA response
and a markedly decreased level of noradrenaline in the peripheral bloo
d were observed in chickens treated with 400 mu g of 6-OHDA at 14 days
of incubation. These results suggested the immunomodulatory influence
of the sympathetic nervous system.